{"version":"1.0","provider_name":"PepZinGI Official Website","provider_url":"https:\/\/www.pepzingi.com\/pzg","author_name":"grab8do","author_url":"https:\/\/www.pepzingi.com\/pzg\/author\/grab8do\/","title":"Scientific Literature - PepZinGI Official Website","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"AuJkJHika6\"><a href=\"https:\/\/www.pepzingi.com\/pzg\/scientific-literature\/\">Scientific Literature<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/www.pepzingi.com\/pzg\/scientific-literature\/embed\/#?secret=AuJkJHika6\" width=\"600\" height=\"338\" title=\"&#8220;Scientific Literature&#8221; &#8212; PepZinGI Official Website\" data-secret=\"AuJkJHika6\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script type=\"text\/javascript\">\n\/* <![CDATA[ *\/\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/www.pepzingi.com\/pzg\/wp-includes\/js\/wp-embed.min.js\n\/* ]]> *\/\n<\/script>\n","description":"Mechanism of Action PepZinGI\u2122, a novel crystalline chelate compound consisting of L-carnosine (N-&beta;-alanyl-L-histidine) and zinc, was first invented by Hamari Chemicals, Ltd. in 1983 aiming at combining the two physiologically important substances in one entirely new molecule[1]. This special chelated form of the mineral zinc has a unique ability to exert its effects directly on the cells of the stomach lining. When zinc is complexed to L-carnosine, it dissociates in the stomach at a slower rate. This prolonged existence allows it to maintain its gastric healing effect over a longer period of time[2]. The dipeptide L-carnosine is found mainly in the muscles of vertebrate and zinc is an essential trace element which plays an important role in the body, for example at the active centers of over 300 enzymes [3]. Both L-carnosine and zinc have common pharmacological properties such as anti-oxidant, membrane stabilizing, immunomodulating, and tissue repairing effects, and their anti-ulcerogenic effects in animals have also been investigated independently [4][5]. After extensive pharmacological studies PepZinGI\u2122 was found to have a unique anti-ulcer property with both cytoprotective and tissue repairing actions in acute and chronic ulcers. Various action mechanisms such as anti-oxidant[6], membrane stabilizing[7], prostaglandin-independent cytoprotective[8], wound healing[9] and anti-Helicobacter pylori[10] activities have been proposed for the anti-ulcer effect. The most featured character of PepZinGI\u2122 is that it adheres specifically to the ulcer legions and remains there for a long time[11], suggesting that this property plays a key role to heal ulcer. Various toxicological studies[12], on the other hand, proved that this compound has enough safety to undergo clinical evaluation. In a controlled double blind clinical study for gastric ulcer patients, PepZinGI\u2122, an 8-week treatment showed significantly better effect than those of cetraxate hydrochloride, with little side effect[13]. Thus a new drug application for PepZinGI\u2122, both for the active ingredient and [&hellip;]","thumbnail_url":"https:\/\/www.pepzingi.com\/pzg\/wp-content\/uploads\/sites\/14\/2020\/05\/science-image.png"}